英文背景介绍：

Glutathione is a small peptide composed of three amino acids: cysteine, glutamic acid, and glycine and is present in tissues in concentrations as high as one millimolar. It contains an unusual peptide linkage between the amine group of cysteine and the carboxyl group of the glutamate side chain. Glutathione is involved in detoxification, it binds to toxins, such as heavy metals, solvents, and pesticides, and transforms them into a form that can be excreted in urine or bile. It is also an important antioxidant, helping to maintain the -SH groups of proteins in their reduced form. Chronic functional glutathione deficiency is associated with glucose 6-phosphate dehydrogenase deficiency, immune disorders, an increased incidence of malignancies, and in the case of HIV disease, probably accelerated pathogenesis of the disease. Acute manifestations of functional glutathione deficiency can be seen in those who have taken an overdosage of acetaminophen (paracetamol). This results in depletion of glutathione in the hepatocytes, leading to liver failure and death.

 

中文背景介绍：

谷胱甘肽是一种由三种氨基酸组成的小肽：半胱氨酸、谷氨酸和甘氨酸，存在于组织中的浓度高达一毫摩尔。它含有半胱氨酸的胺基和谷氨酸侧链的羧基之间的不寻常的肽键。谷胱甘肽参与解毒，它与重金属、溶剂和杀虫剂等毒素结合，并将它们转化为可以在尿液或胆汁中排泄的形式。它也是一种重要的抗氧化剂，有助于维持蛋白质的 -SH 基团的还原形式。慢性功能性谷胱甘肽缺乏症与葡萄糖6-磷酸脱氢酶缺乏症，免疫紊乱，恶性肿瘤发病率增加有关，并且在HIV疾病的情况下，可能加速了疾病的发病机制。功能性谷胱甘肽缺乏症的急性表现可见于服用过量对乙酰氨基酚（扑热息痛）的患者。这导致肝细胞中谷胱甘肽的消耗，导致肝衰竭和死亡。

 

产品名称别名：

Glutathione antibody

GSH antibody

Oxidised glutathione antibody

Reduced glutathione antibody

 

产品货号：101-A

产品品牌：Virogen

品牌代理：靶点科技