推荐产品
新闻中心/正文
Kerafast的ENH001抗体Anti-DNA-RNA Hybrid [S9.6] Antibody 现货促销!!!
人阅读 发布时间:2022-07-16 19:59
Kerafast ENH001 Anti-DNA-RNA Hybrid [S9.6] Antibody 针对ΦX174噬菌体衍生的合成DNA-RNA抗原产生该小鼠单克隆抗体,并识别各种长度的RNA-DNA杂交体。
产品特色:
- 对DNA-RNA杂交体具有高度特异性和亲和力
- 可用于检测R环
- 不与单链DNA或双链DNA交叉反应
- 对于富含AU的双链RNA,已观察到轻微的交叉反应(约5倍)。
- 对于长度为8,10,15和23个碱基对的杂交体显示出高亲和力结合
DNA-RNA杂合体是真核细胞中的天然存在,这些za种的水平在具有高转录活性的位点增加,例如在转录起始,抑制和延伸期间。由于RNA-DNA杂交体影响基因组不稳定性,S9.6抗体是一种有用的试剂,可帮助研究这些za种在DNA复制或其他细胞过程中形成的R环和损伤的后果。此外,S9.6抗体可有效识别用于微阵列研究的RNA-DNA杂交。
背景介绍:
DNA-RNA hybrids are a natural occurrence within eukaryotic cells, with levels of these hybrids increasing at sites with high transcriptional activity, such as during transcription initiation, repression, and elongation. Because RNA-DNA hybrids influence genomic instability, the S9.6 antibody is a useful reagent to help study the consequences of R-loops and lesions formed by these hybrids during DNA replication or other cellular processes. In addition, the S9.6 antibody is effective in recognizing RNA-DNA hybridization for microarray studies。
产品详情:
Product Type: | Antibody |
Name: | Anti-DNA-RNA Hybrid [S9.6] |
Antigen: | S9.6 ΦX174 bacteriophage-derived synthetic DNA–RNA antigen |
Isotype: | Rabbit IgG |
Fusion Tag(s): | Mouse Fab version contains His-tag |
Clone Name: | S9.6 |
Reactivity: | High specificity and affinity for DNA/RNA hybrids and other A-form nucleic acid hybrids |
Immunogen: | ΦX174 bacteriophage-derived synthetic DNA/RNA |
Purification Method: | Protein A/G |
Buffer: | ENHOO1: PBS, 0.05% (w/v) Sodium Azide Ab01137- : PBS with 0.02% Proclin 300 |
Tested Applications: | Dot Blot Analysis: 0.2 µg/mL. |